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Results for list or group "Living Organisms on the Domestic Substances List"

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Showing 151 to 200 of 224 entries | entries

List or group: Living Organisms on the Domestic Substances List
Substance identifier: ATCC 13525
Substance identifier (2):
Substance name: Pseudomonas fluorescens
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 150, No. 14, July 13 2016, SOR/2016-159
Date published: 2016-07-13
Substance identifier: ATCC 31483
Substance identifier (2):
Substance name: Pseudomonas putida
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette, Part II, Vol. 152, No. 11, May 30 2018, SOR/2018-96
Date published: 2018-05-30
Substance identifier: ATCC 31800
Substance identifier (2):
Substance name: Pseudomonas putida
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette, Part II, Vol. 152, No. 11, May 30 2018, SOR/2018-96
Date published: 2018-05-30
Substance identifier: ATCC 12633
Substance identifier (2):
Substance name: Pseudomonas putida
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette, Part II, Vol. 152, No. 11, May 30 2018, SOR/2018-96
Date published: 2018-05-30
Substance identifier: ATCC 700369
Substance identifier (2):
Substance name: Pseudomonas putida
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette, Part II, Vol. 152, No. 11, May 30 2018, SOR/2018-96
Date published: 2018-05-30
Substance identifier: ATCC 13867
Substance identifier (2):
Substance name: Pseudomonas sp.
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 139, No. 18, September 07 2005, SOR/2005-236
Date published: 2005-09-07
Substance identifier: 19827-5
Substance identifier (2):
Substance name: Pseudomonas species bacteriophage QP-PSA-006
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 160, No. 11, June 3, 2026, SOR/2026-85
Date published: 2026-06-03
Substance identifier: 19828-6
Substance identifier (2):
Substance name: Pseudomonas species bacteriophage QP-PSA-007
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 160, No. 11, June 3, 2026, SOR/2026-85
Date published: 2026-06-03
Substance identifier: 19829-7
Substance identifier (2):
Substance name: Pseudomonas species bacteriophage QP-PSA-009
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 160, No. 11, June 3, 2026, SOR/2026-85
Date published: 2026-06-03
Substance identifier: ATCC 17587
Substance identifier (2):
Substance name: Pseudomonas stutzeri
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 139, No. 18, September 07 2005, SOR/2005-236
Date published: 2005-09-07
Substance identifier:
Substance identifier (2):
Substance name: Recombinant adeno-associated virus (AAV) containing AAV-LK03 capsid (AAV-Spark200) and encoding the SQ variant of B-domain deleted human factor VIII
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 157, No. 7, March 29 2023, SOR/2023-50
Date published: 2023-03-29
Substance identifier:
Substance identifier (2):
Substance name: Recombinant and non-replicating adeno-associated virus encoding the chimeric ion channel m-α7-GlyR (RP-008)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 158, No. 6, March 13 2024, SOR/2024-38
Date published: 2024-03-13
Substance identifier:
Substance identifier (2):
Substance name: Recombinant and non-replicating adeno-associated virus serotype 5 (AAV5) vector containing the codon-optimized coding DNA sequence for the human coagulation factor IX variant R338L (FIX-Padua)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 159, No. 6, March 12, 2025, SOR/2025-58
Date published: 2025-03-12
Substance identifier:
Substance identifier (2):
Substance name: Recombinant and non-replicating adeno-associated virus serotype 5 (AAV5) vector expressing a retinitis pigmentosa GTPase regulator gene RPGR (AAV5-hRKp.RPGR)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol.157, No.16, August 2, 2023, SOR/2023-166
Date published: 2023-08-02
Substance identifier: 19790-8
Substance identifier (2):
Substance name: Recombinant and non-replicative adeno-associated virus 2/8 producing a modified protein phosphatase inhibitor 1
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 159, No. 20, September 24, 2025, SOR/2025-184
Date published: 2025-09-24
Substance identifier:
Substance identifier (2):
Substance name: Recombinant and non-replicative adeno-associated virus serotype 4D-R100 carrying a miRNA targeting VEGF-C and expressing the aflibercept protein (4D-150)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 159, No. 27, December 31, 2025, SOR/2025-254
Date published: 2025-12-31
Substance identifier:
Substance identifier (2):
Substance name: Recombinant and non-replicative adeno-associated virus serotype 5 encoding a human NR2E3 gene (OCU400)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 159, No. 19, September 10, 2025, SOR/2025-179
Date published: 2025-09-10
Substance identifier:
Substance identifier (2):
Substance name: Recombinant and non-replicative adeno-associated virus serotype 8 (rAAV8) expressing a humanized anti-vascular endothelial growth factor (VEGF) antibody fragment (RGX-314)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 157, No. 21, October 11, 2023, SOR/2023-201
Date published: 2023-10-11
Substance identifier:
Substance identifier (2):
Substance name: Recombinant and non-replicative adeno-associated virus serotype 8 (rAAV8), producing the aflibercept protein (NG101)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 157, No. 25, December 6 2023, SOR/2023-252
Date published: 2023-12-06
Substance identifier:
Substance identifier (2):
Substance name: Recombinant and non-replicative adeno-associated virus serotype rh74 containing a shortened human dystrophin gene (SRP-9001)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 159, No. 20, September 24, 2025, SOR/2025-184
Date published: 2025-09-24
Substance identifier:
Substance identifier (2):
Substance name: Recombinant and non-replicative adeno-associated virus serotype SLB101 expressing a genetically modified human microdystrophin gene (SGT-003)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 159, No. 19, September 10, 2025, SOR/2025-171
Date published: 2025-09-10
Substance identifier:
Substance identifier (2):
Substance name: Recombinant and non-replicative chimpanzee adenovirus-serotype 68 expressing a trivalent transgene coding for SARS-CoV-2 spike-nucleoprotein-polymerase (ChAd-TriCoV/Mac)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 158, No. 20, September 25 2024, SOR/2024-173
Date published: 2024-09-25
Substance identifier:
Substance identifier (2):
Substance name: Recombinant and non-replicative human adenovirus-serotype 5 expressing a trivalent transgene coding for SARS-CoV-2 spike-nucleoprotein-polymerase (Ad5-TriCoV/Mac)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 158, No. 20, September 25 2024, SOR/2024-173
Date published: 2024-09-25
Substance identifier:
Substance identifier (2):
Substance name: Recombinant and non-replicative single-stranded adeno-associated viral vector of serotype 2 expressing a soluble human CD59 gene (AAVCAGsCD59)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 158, No. 9, April 24 2024, SOR/2024-56
Date published: 2024-04-24
Substance identifier:
Substance identifier (2):
Substance name: Recombinant and replication-competent vaccine based on vesicular stomatitis virus with the VSV G-protein removed and replaced with the Ebola virus envelope glycoprotein (rVSVΔG-ZEBOV-GP)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 157, No. 14, July 5 2023, SOR/2023-145
Date published: 2023-07-05
Substance identifier: 19349-7
Substance identifier (2):
Substance name: Recombinant human autologous T lymphocyte expressing a chimeric antigen receptor for human B cell maturation antigen
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 153, No. 13, June 26 2019, SOR/2019-209
Date published: 2019-06-26
Substance identifier:
Substance identifier (2):
Substance name: Recombinant human Herpes Simplex Virus encoding human Granulocyte Macrophage Colony-Stimulating Factor and the Gibbon Ape Leukaemia Virus surface GlycoProtein with R-sequence deleted
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 157, No. 21, October 11, 2023, SOR/2023-201
Date published: 2023-10-11
Substance identifier:
Substance identifier (2):
Substance name: Recombinant human mesenchymal stromal cells with a non-viral plasmid expressing the angiopoietin and acyloxyacyl hydrolase genes (GEM00220)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 156, No. 1, January 5 2022, SOR/2021-264
Date published: 2022-01-05
Substance identifier: 19624-2
Substance identifier (2):
Substance name: Recombinant human T lymphocyte expressing a CD19-specific chimeric antigen receptor (CC-97540)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 156, No. 24, November 23, 2022, SOR/2022-233
Date published: 2022-11-23
Substance identifier: 19528-6
Substance identifier (2):
Substance name: Recombinant human T lymphocytes expressing a CD19-specific chimeric antigen receptor
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 155, No. 17, August 18 2021, SOR/2021-180
Date published: 2021-08-18
Substance identifier: 19703-1
Substance identifier (2):
Substance name: Recombinant human T lymphocytes expressing a CD19-specific chimeric antigen receptor (TBI-2001)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 158, No. 9, April 24 2024, SOR/2024-56
Date published: 2024-04-24
Substance identifier:
Substance identifier (2):
Substance name: Recombinant human T-cells expressing an anti-CD19/anti-CD20 chimeric antigen receptor transgene (JNJ-90014496)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 159, No. 19, September 10, 2025, SOR/2025-171
Date published: 2025-09-10
Substance identifier:
Substance identifier (2):
Substance name: Recombinant human T-cells transduced with a non-replicative lentiviral vector expressing a chimeric antigen receptor binding the human B-cell CD19 antigen (ALLO-501A)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 158, No. 4, February 14 2024, SOR/2024-5
Date published: 2024-02-14
Substance identifier:
Substance identifier (2):
Substance name: Recombinant human T-cells transduced with a non-replicative lentiviral vector expressing a chimeric antigen receptor binding the human B-cell maturation antigen (PHE885)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 158, No. 9, April 24 2024, SOR/2024-56
Date published: 2024-04-24
Substance identifier:
Substance identifier (2):
Substance name: Recombinant live-attenuated dengue virus serotype 1 modified from strain Western Pacific (rDENV1Δ30 -V181)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 157, No. 7, March 29 2023, SOR/2023-50
Date published: 2023-03-29
Substance identifier:
Substance identifier (2):
Substance name: Recombinant live-attenuated dengue virus serotype 2 modified from strain New Guinea C (rDENV2/4Δ30(ME)-V181)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 157, No. 7, March 29 2023, SOR/2023-50
Date published: 2023-03-29
Substance identifier:
Substance identifier (2):
Substance name: Recombinant live-attenuated dengue virus serotype 3 modified from strain Slemen/78 (rDENV3Δ30/31 -V181)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 157, No. 7, March 29 2023, SOR/2023-50
Date published: 2023-03-29
Substance identifier:
Substance identifier (2):
Substance name: Recombinant live-attenuated dengue virus serotype 4 modified from strain Dominica/81/814669 (rDENV4Δ30 -V181)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 157, No. 7, March 29 2023, SOR/2023-50
Date published: 2023-03-29
Substance identifier:
Substance identifier (2):
Substance name: Recombinant non-replicating adeno-associated virus serotype 6 vector encoding B-domain deleted human coagulation Factor VIII (PF-07055480)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 157, No. 11, May 24 2023, SOR/2023-90
Date published: 2023-05-24
Substance identifier:
Substance identifier (2):
Substance name: Recombinant non-replicating adeno-associated virus serotype 9 (AAV9) vector encoding human iduronate-2-sulfatase gene (RGX-121)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 157, No. 1, January 4 2023, SOR/2022-270
Date published: 2023-01-04
Substance identifier:
Substance identifier (2):
Substance name: Recombinant non-replicating Human adenovirus C, EI/E3 deleted, encoding for a human interferon alpha-2b cDNA driven by cytomegalovirus and adenovirus type 2 tripartite leader
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 154, No. 26, December 23 2020, SOR/2020-274
Date published: 2020-12-23
Substance identifier:
Substance identifier (2):
Substance name: Recombinant non-replicating human adenovirus type 26 encoding the severe acute respiratory syndrome coronavirus 2 Spike protein (Ad26.COV2.S)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 155, No. 11, May 26, 2021, SOR/2021-98
Date published: 2021-05-26
Substance identifier: 19493-1
Substance identifier (2):
Substance name: Recombinant paramyxovirus encoding transgene (MRK-RPET-001)
Additional information: This substance is a living organism.

The Public Health Agency of Canada (PHAC) has classified this biological agent as a human and/or terrestrial animal pathogen. Under the Human Pathogens and Toxins Act (HPTA), controlled activities with human pathogens that are classified as Risk Group 2-4 require a licence, issued by PHAC. PHAC is also responsible for issuing permits for the importation of pure cultures of terrestrial animal pathogens of Risk Group 2-4, with the exception of non-indigenous animal pathogens and pathogens causing emerging animal disease, under the authority of the Health of Animal Regulations (HAR). For a listing of Risk Group classifications of biological agents in Canada, visit ePATHogen - Risk Group Database.

Please contact pathogens.pathogenes@phac-aspc.gc.ca for further information.

Please note: The Canadian Food Inspection Agency (CFIA) has the authority under the Health of Animals Act and the Health of Animals Regulations to issue importation permits for animals, animal products and by-products, aquatic animal pathogens, bee pathogens, pathogens causing foreign animal diseases, and pathogens causing emerging animal diseases. The CFIA also issues import permits for plant pests under the Plant Protection Act.
Recent publication(s): Canada Gazette Part II, Vol. 154, No. 26, December 23 2020, SOR/2020-274
Date published: 2020-12-23
Substance identifier:
Substance identifier (2):
Substance name: Recombinant replication-defective chimpanzee adenovirus ChAdOx1 expressing the glycoprotein E gene from the varicella-zoster virus (ChAdOx1-VZV)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 157, No. 25, December 6 2023, SOR/2023-252
Date published: 2023-12-06
Substance identifier:
Substance identifier (2):
Substance name: Recombinant replication-defective chimpanzee adenovirus Ox1 expressing Spike protein (S protein) of SARS-CoV-2 (ChAdOx1-S)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 155, No. 14, July 7, 2021, SOR/2021-159
Date published: 2021-07-07
Substance identifier:
Substance identifier (2):
Substance name: Recombinant replication-deficient adeno-associated viral vector serotype 2 expressing the human retinal pigment epithelium protein (rAAV2-hRPE65v2-LTW888)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 157, No. 11, May 24 2023, SOR/2023-90
Date published: 2023-05-24
Substance identifier:
Substance identifier (2):
Substance name: Recombinant replication-incompetent adeno-associated viral vector serotype 9 expressing β-hexosaminidase genes (ssAAV9-CAG-HEXBP2AHEXA)
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 160, No. 7, April 8, 2026, SOR/2026-52
Date published: 2026-04-08
Substance identifier:
Substance identifier (2):
Substance name: Recombinant, chimeric vesicular stomatitis virus (VSV) carrying the envelope glycoprotein (GP) of the visceral non-neurotropic WE-HPI strain of the lymphocytic choriomeningitis virus, and a codon-optimized human CD80 gene fused to the Fc IgG1 heavy chain constant region
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 158, No. 11, May 22, 2024, SOR/2024-83
Date published: 2024-05-22
Substance identifier:
Substance identifier (2):
Substance name: Recombinant, chimeric vesicular stomatitis virus carrying the envelope glycoprotein of the visceral non-neurotropic WE-HPI strain of the lymphocytic choriomeningitis virus
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 160, No. 4, February 25, 2026, SOR/2026-27
Date published: 2026-02-25
Substance identifier:
Substance identifier (2):
Substance name: Replication-incompetent chimpanzee-derived Simian mastadenovirus C serotype 155 expressing human respiratory syncytial virus A2 (HRSV-A2) antigens F, N and M2-1
Additional information: This substance is a living organism.
Recent publication(s): Canada Gazette Part II, Vol. 152, No. 26, December 26 2018, SOR/2018-271
Date published: 2018-12-26
Date modified: